NSF SBIR Phase I Grant

NSF SBIR Phase IIA Supplemental Funding Grant

Mesa has been awarded a NSF SBIR Phase IIA Supplemental Funding grant in collaboration with the New Mexico State University CREST Bioinformatics and Computational Biology Center.  This is an approximately 1 year supplement starting August 15, 2006.  The goal is to develop a three dimensional protein prediction virtual classroom module, and thereby provide a bioinformatics add-on to the three dimensional drug design module of the Phase II project (see link to NSF Phase II award below for more information). 

NSF SBIR Phase II Grant

"Cheminformatics Teaching Tools for the Cheminformatics Virtual Classroom" commencing, March 1, 2005.

<http://nsf.gov> Our research results are based upon work supported by the National Science Foundation Small Business Innovation Research (SBIR) Program under Grant No. 0450457. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation (abstract
<http://www.nsf.gov/awardsearch/showAward.do?AwardNumber=0450457>)--Mesa Analytics & Computing, LLC

NSF awards SBIR grants to small businesses for risky, novel research with a potential for commercialization. Through SBIR and the related Small Business Technology Transfer (STTR) programs, NSF encourages partnerships between the small business and the academic sectors to develop a technology base for commercialization.

See the Cheminformatics Virtual Classroom homepage: http://www.chemvc.com

Software

• ChemTattoo^TM, a substructure commonality tool using OEChem 1.3.1, runs with either Openeye's Ogham or Chemaxon Marvin Tools for 2D depiction.
• Mesa's Fingerprint Module now runs on OEChem 1.4.0 from OpenEye Scientific Software, and come in both standalone executables and library function forms.
• Fingerprint and Grouping Module Theory Manuals now online in Products section.
• Fingerprint and Grouping Module programs come in both standalone executables and library function forms
• Grouping Module now contains Hierarchical (including Level Selection Techniques), Kmeans/Kmodal, and Jarvis Patrick clustering with ambiguity measures.  Kmeans/Kmodal and Jarvis Patrick also come in disjoint and non-disjoint clustering forms.
• Grouping Module is now PVM enabled for very large data sets.
  

Upcoming Releases

• SAESAR:  Shape and Electrostatics with Structure Activity Relationship.  March 2007
  
• New Mesa Key Fingerprinter and corresponding ChemTattoo version.  April 2006.
• ChemVC:  Cheminformatics Virtual Classroom.  August 2007.

Upcoming Presentations

•  ACS National Spring National Meeting in Chicago, CINF Session, March 24-28, 2007
  

• Substructure commonality analysis and visualization with new key-based binary fingerprinter, Norah MacCuish and John MacCuish
  

The Press Room:

AccuSoft Tools Aim to Speed Drug Discovery

OpenEye Scientific Software, Inc and Mesa Collaboration Press Release